Soccer and pumping - additional conclusions

Since starting the experiment on pumping I have had some issues when playing soccer (BG's that piss me off, and Soccer and pumping). My nurse has been convinced that the high BG's that I see after a game, where I have been disconnected for 1-2.5 hours, were mainly due to release of "fight"-hormone (adrenaline) during the game, and not the period of time being disconnected. I was not too sure about that conclusion, though I certainly agree that the adrenaline probably does take part in the high-party. I have found that adding Lantus and Actrapid to my insulin regimen on game days have almost eliminated the problem, which makes me even more convinced that the post-game hyperglycemia issues that I have been experiencing running solely on NovoRapid from my pump and being disconnected 2-3 times longer than recommended in the manual, are not a mere result of excessive adrenaline release. Today at work we had "Activity Day" in our department. This arrangement was arranged by the department's social committee with the purpose of making all the staff and students get together and enjoy a summer afternoon with games and chatting around the barbeque. Thus, we only had to work until noon, and then we all meet outside on the grass for dart, croquet, petanque, vikingespil, soccer, volleyball and foot-tennis. Of course I was up for a soccer game together with quite a few other people from my group. We set up a field on the rough (this part of the lawn is seemingly not mowed as often as those parts were fields were set up for vikingespil, petanque, croquet and dart!) and played two halfs - we needed a break and a drink (the department hosted the barbeque along with plenty of beer and some soft drinks to enjoy before, during and afterwards) :-) I guess that we played something like 30 and 45 minutes, but I really don't know because I didn't check the clock while playing, so it may actually have been longer than that. As always, when playing soccer, I disconnect. I reconnected during our break though. During the second game I didn't feel that fit, suspecting a hypo comming along, so, because I hate stopping in the middle of something, I just consumed half a packet of glucose tabs not leaving the game. When we stopped, I tested just before the barbeque was ready: 3.8 (68). Well, the hypo during the game seemed to be true and I was still on the low side, so I ate some raisins while waiting for the sausages and bread on the two grills to be eatable. About 14.30 PM food was ready. I was not really that hungry as I had an early lunch before the beginning of the activities, but I wouldn't miss the sausages. I only had one though, along with one bread, and figured that a bolus of 1 unit should cover that. A couple of hours later, when getting ready to go home, I tested 9.0 (162). Why??? I didn't really give more thought to it, I was a bit hungry so I bolused 2.3 units (wizard's recommendation) for a bun, ate it and hit the road on my bike. The 2.3 units for the bun is usually more than enough to cover it, especially when going on a 9 km bike ride afterwards, but when I tested before dinner 1.5 h later I was 216!!! By this time I realized that maybe, because I didn't take any Lantus in the morning to cover the periods of time being disconnected during the games, I was probably experiencing the post-game hyperglycemia effect that I have become familiar with since starting the pump. As far as I can tell, I didn't go as high as I have sometimes been following games, which may give adrenaline the honor of throwing the readings through the roof after all, because as the intensity of the games today was not as high as in our games of the tournament, the adrenaline release was probably lighter. Still, I dare to say that this also proves that adrenaline is not the only culprit in this post-game hyperglycemia game, it just does take part.

For the record, by 19.30 PM I was back in range at 4.5 (81) again, so eventhough it required a larger bolus for my dinner this post-game hyperglycemia attack was not as stubborn as previously seen :-) Now it is time for the final reading before going to bed, I hope this one is just as good as the previous one!

My week....

Another busy week has past by. Thursday I had an endo-appointment, which didn't provide any new ideas as to the issues I feel I have been having with pumping insulin. My doctor (MK) did not appear to be that familiar with pump therapy - just amazed of how the pump and infusion site look like nowadays, compared to years ago - and we agreed that I should continue working with the nurse. At the end of my appointment MK asks me if I feel we are getting too close (MK was my co-supervisor during my Master's project, and we have kept contact afterwards because he felt that some of the results I obtained should be published), if I felt I could not talk openly to him because he knew me more than just as a patient and would be more comfortable changing to a new doctor. I was a bit amazed about these questions, although we have discussed it previously, but I told him, as is the truth, that it was not a problem for me as long as we could keep things apart at my endo appointments, i.e. that the time is primarily used to solve diabetes related issues, not experimental or paper issues. That has unfortunately been the case at some appointments, especially if it had been a long time since we have meet scientifically, but this time it was not, and MK agreed to focus on separating the two fields of discussions.

After the endo appointment, I had a 2 H meeting with a clinical professor and his associate professor along with a couple of people from my lab. Our quest was to promote mass spectrometry in general, and particularly our knowledge of this area, to these professors as they had announced at least one opening for a Ph.D. position at the end of this year, something that we would like get into. The meeting went very well, so we are all hopeful that it will result in them hiring at least one of us for projects in the future.

Friday was the traditional Danish Midsummer Eve, where people usually join at bonfires to "send witches towards Bloksbjerg". Jimmi and I had talked about going to the large meadow in Odense where the largest bonfire of the city was set, but we ended up just staying at home for several reasons. Jimmi has just been sent on sick leave from work due to a work-related back injury he got back in December and he wasn't really up to taking the 8 km trip to the meadow just to look at a bonfire when there was World Cup soccer in the television. We also needed to go shopping for something to eat for breakfast the next day. Going to the supermarket for this, we were also determined that at least we would celebrate the evening by buying some fresh Danish strawberries (strawberries and midsummer is closely related in Denmark). So we had our first Danish strawberries of the year along with ice cream - uhmm!!! But first I had to treat a stubborn low that made me get off my bike on the way back from the supermarket, because my arms and legs were not cooperative. Grrr!!!

Saturday was just a quiet day used for house work and a trip to the Rosengaardscenter, a large shopping mall in the south eastern part of Odense. I went there because I didn't manage to go to the pharmacy in the morning, and on Saturdays most of the pharmacies closes at noon, but the one in the mall is open until 2 PM which gave me time to fill a prescription on insulin. They did not have the 3 bottles that my presciption entitles me to get each time, I could only get 1, but that was actually ok because I realized that I had just started all over on the annual medical grant arrangement, meaning that I have to pay full price for the medicine up to 480 kr. (approximately 80 dollars) before I start getting the tiered grant again :-(

Sunday was a very hot and sunny day. We had the last soccer game of the spring season at 10.45 AM, playing on a field properly shielded for the wind by close-grained trees and bushes. That was tough because there wasn't any shadow what so ever on the field during the game, so we felt like it was almost impossible to replenish the water lost by sweating without camel packs on our backs (just imagine how that would look if 22 players were running around with a straw in their mouth from camel packs on their backs ;-)). Unfortunately we lost the game, but overall we can be very happy with our spring season as we stayed in the league that we were promoted to last fall, ending 5 th. of 10 teams.

Whether it was the heat, all the soccer (requiring the use of Lantus to be able to stay off the pump for a suitable amount of time) and bicycling being performed on Sunday or whatever, the night between Sunday and Monday I experienced another severe low. Jimmi woke up at about 1 AM because I was taking up an awful lot of space in the bed. When he wanted to make me move, he noticed I was all limb and sweaty, figuring that I must be low. He started feeding me glucose tabs patiently awaiting my awakening, but it didn't come. After almost an hour and a whole pack of glucose tabs, I still seemed unresponsive so he did a a BG-test that showed 2.3 mmol/l (41). Sure too low, and being worried that all the glucose he had stuffed me with did have any effect, he decided to call 112 (911 in the US). I think that I remember them arriving though, despite I was very sleepy and thus hoping that it was just a dream. Anyway, besides the two paramedics this time there was also a doctor and a nurse along - our bedroom was suddenly quite crowded! I don't know why the latter two had been called, but I guess that I should just be happy about that because it meant that instead of getting a glucagon shot, which tend to make me very sick afterwards, I got IV-glucose in stead, lifting the BG from 2.6 (47) at their arrival to 7.1 (128) at their departure - and I didn't have to go to the hospital. The episode did destroy my night's sleep though, because I could not go back to sleep after they left. I tossed and turned for at least 1 H, feeling like the BG was about to go through the roof - and it was on its way up there being 16.5 (297) when testing, so I did a correction of 4 units and finally fell asleep, only to wake up with difficulty about 1.5 H later with symptoms of being low again. I didn't test, just ate a couple of glucose tabs, lowered the pump basal and immediately got back to sleep - for 1 H then the alarm clock announced that it was time to get up and go to work :-( BG 5.4 (97), though, so that was at least a small victory. These are the time when I really, really HATE this f...... disease - and the inability of me to control the BG just as well as the non-diabetic body can!

Because of the lack of sleep, I was happy that my Monday was not that challenging. I had an ongoing mail correspondence with MK about the paper that I am trying to write - he is reading my draft these days, hopefully providing me with some ideas and critics to go on with - and other wise just did some data analysis before going to a Master's defense at MK's lab in the afternoon. I did not want to go back to work when the defense was over - it is a 30 min bike ride for maybe 1 H more at the computer - so I was back home at astonishing 4 PM! Because of this, we decided to have an early dinner and then head for the movies to see the last movie of the season with our Cinema Club tickets. It was a Danish movie about a guy, Jorgen, being responsible for the lottery club at work. Every time he bought coupons for the lottery club, he would also buy one for his wife, dog-earing it to make sure he could tell them apart. The lottery club usually never win anything, but one day when Jorgen checks the coupons he realizes that they have a full lottery win of 3.5 mill. kr (583,000 dollars). They are 6 guys in the club, so they will each get plenty of money out of this win, yet Jorgen starts to think that he and his wife deserve all the money themselves. This causes them to enter a cycle of lies and excuses about their actions. It wears them down, Jorgen in particular, and he end up telling the other guys of the lottery club the truth. They tell him that he is an idiot, any of them would have kept all the money themselves, and thus it is sort of a happy ending with a clear moral that cheating and lying just doesn't pay. Quite a good movie, also because you could relate to the lives and struggles of the main characters, including the thought about what you would do if you suddenly became a millionaire in the lottery (if you play the lottery, that is ;-)).

Yesterday was plane desk work with a lot of not too encouraging data analysis, which I have continued doing today. However, the biweekly group meeting, which we had today, sort of cut the day in half because it starts at 10 AM and usually takes a couple of hours. This means that you get away from what you have been doing, and for me this made the data analysis I needed to return to even more boring, which is why I am not taking the time to white this long post eventhough I ought to be searching spectra :-) Well, maybe I should just get back to work now!

Another meme

I haven't been too good at posting on a regular basis. I simply haven't taken the time to do it. Work takes a lot of time - even though I sometimes take a break and spent it on the Internet, as just now ;-) - and in the evenings I hardly turn on the computer because I either have soccer practice/games to attend, want to enjoy the decent summer weather we have at the moment, and/or follow the World Cup games on TV (yes, I am a soccer freak, and I do enjoy watching soccer almost as much as playing it myself, although it is sad that Denmark is not among the participants in the current World Cup). Still, I do manage to spent a few minutes now and then catching up on some of the diabetes related blog that I like to read. One of them (http://lalashilolog.blogspot.com/2006/06/highs-and-lows-of-pumping-newbies.html) inspired me to make this post on the "Highs and lows of pumping".

I am approaching the end of the initial 3-month pump-try-out that I reluctantly agreed upon in March. I was set up on April 6 and my now have 2.5 months of experience and learning with pump therapy. As MDI therapy is still fresh in my memory, I cannot help to compare the two regimes.

Highs of pumping:

1. A great advantage when I was in Prague for a conference in the beginning of May. Not knowing was to expect from lunch would have been a bit tricky with injections, as I preferred to use Actrapid (Regular) for meals, thus usually would do the injection 15-30 min. before starting to eat. With the pump it was just take a look on that lunch pack you were handed, estimate the amount of insulin needed to cover it and then GO!
2. Even more flexibility than I had with injections as far as to when and what I eat.
3. Unexpected temptations (food-wise) can be handled - though when on injections, I would usually carry at least a fast-acting insulin pen with me, there have been time where I did not expect to be out during meal time and therefore did not bring any along, thus needing to moderate my intake of food significantly, or simply say no, because I could not bolus for it.

Lows of pumping:

1. Adjusting the basals, parameter for the wizard function ect. is a living nightmare! When I started the pump, I did expect it to take some time before these things were settled, but I did not expect it to take as long as it did - it is actually not settled completely yet, though it is far more acceptable now than just a month ago. I know I ought to go through these fasts in order to check how the basals match my need, and I have completed the night-to-lunch fasts, but it has been hard and actually I ought to repeat them as I have changed the basals in order to get closer to my target range than the initial basal would get me. My problem with these fasts are that I am very active every day so I get hungry if I do not eat regularly. If I am fasting while hungry, I can't focus on what I should be doing (work ect.), which is not very effective. My nurse, Alice, understands this, fortunately, but her colleague, who started me up because Alice was on vacation, did not. She actually suggested that I just lay off some of the activity until the basals were set, but I argued against this for several reasons. First, and most importantly, I can't see how you can use resultsobtainedd on a "lazy day" to regulate the basals needed for usual week days where I bike 20-40 km and/or play soccer practicee or game)! Second, I do not have the patience to commute by city busses to get to work. I have had enough of commuting by train and busses the first years of my study, and as we don't have a car, I would rather spent 25-30 min. on my bike in the mornings and afternoons than twice the amount of time in different city busses to get from my home to work and back again.
   
2. Pumping is so incompatible with my soccer games! I virtually never had any great troubles with game days when using MDI, but with the pump, I have experienced nothing but trouble controlling BG's. I am usually able to start out pretty good, and a few time I have even managed to be in range just after the game as well, but whether or not I am in range just after the match, I can be sure that the BG will sky rocket afterwards. An example: 6.1 mmol/l (110) just after a game, 17.8 mmol/l (320) with beginning ketones and generally feeling lousy just 2 hours later! I am not comfortable with wearing the pump during games, so I disconnect. I also do that atpracticee, which is 1.5 H, approximately the same as a game without the warm-up, and I have no problems with that. I am not sure if the game issue is related to the amount of time being disconnected, fight hormones, or a combination of factors, but I have never had these problems when on injections. The last couple of games I have therefore defied threcommendationsns from the hospital about not involving any other types of insulin when pumping, and taken a shot of Lantus (dose approximatelequalingng 75 % of my pump basal) in the morning and then a shot of actrapid for the last meal I have before the game. I then run my pump basal very low (10-15 %) until the actrapid is out of my system again, then depending on the blood sugar I will raise the pump basal to 25-50 % of normal waiting for Lantus to also leave. So far this has worked nicely for me, having avoided both hypoglycemia before and during the game as well as hyperglycemia afterwards.
3. The pump should in theory even out the swing of your BG, but I havdefinitelyly seen a lot more out of range BG's the last 2.5 months. I know some of them are of cause due to the issues mentioned in item 1 in this Lows-of-pumping-paragraph, but still I am certainly not comfortable with the number of BG's below 2.0 mmol/l (36) that I have obtained in this period of time. I even managed to test as low as my meter just saying "LO", meaning a BG below 1.1 mmol/l (20) - I was certainly not feeling well at that time, and fortunately my boyfriend was there to make sure that I got something to treat that nasty low with.
4. Temptations of delicious and carb-loaded foods can be hard to resist, because bolusing is so easy, not requiring an injection.

This is not a complete list of pro's and con's of pumping for me, but the most important ones for me at the moment. I hope that at least some of the lows will disappear or get less significant by time. I'll let you know what I learn.

Hot, hot, hot

After a week at the Greek island Kos with temperatures above 30 C every day, and difficulties to get temperatures below 28 C in our hotel room at night, we returned to Denmark where temperatures could hardly exceed 18 C during the day. Though we were literally freezing at first, we quickly adapted. However, during last week summer has returned to Denmark, and the last four days this has been with temperatures of 25-30 C. I like summer and sunshine, but I must admit that I prefer temperature not above 25 C, because the air humidity is usually high enough to make the air feel rather heavy.

The hot weather is also - as usual - a challenge for BG-control. I tend to cruise on the low side, but usually I am able to avoid extreme lows by having small meals/snacks every 3-4 H. Sunday Jimmi and I was to take part in a family-get-together-to help-Verner-and-Lotte-shining-up-their-garden. Verner is Jimmi's grandfather, who just had a new hip this winter and therefore is not able to do much gardening yet, so his wife's children had arranged for all the children and grandchildren with their spouses to show up and help with that. We were about 20 people to rearrange the flower beds, paint the garden shed, ect. We started at 10 AM, and as I had just changed site in the morning, I tested before starting the work: 3.4 (61). Hmm, a little too low, maybe due to the 11 km bike ride? I ate a handful of raisins, figuring that to do the trick, and then joined the painting team. We had a short break to eat ice cream later in the morning. I didn't test at that time (I know I should have), just did a small bolus (0.5 U) after consuming the ice. Around 12.30 my boyfriend encourage me to come with him and do a test. I am reluctant to do so, so he almost drag me inside. My memory of it is actually a bit blurred, however I do remember doing the test and seeing the result "LO" on the meter, meaning a BG below 1.1 (20) and thinking "that can't be, I must have used too little blood or something". I can't remember how many glucose tabs I had, but they were followed by a piece of black bread with liver paste. Getting better, I couldn't help being a bit scared by the fact that I actually managed to function, although not that well I admit, and test myself with a BG that low.

Well, I should go back to work. I am analyzing mass spectra at my computer in a very small office that I share with 2 other girls. There is no ventilation in the office and with 3 people and the same number of running computers the temperature is about 35 C, making you sweat even when you are just moving your fingers around the computer keyboard or the mouse.

Off to Kos

I don't feel that I have been at home much this month. When I got back from Prague, I was told that I was hired for two projects in the lab, so I just started a one year full-time position. However, tomorrow, Jimmi and I will be leaving for Kos, a small Greak island for a one week holiday :-)

I am looking forward to a holiday. The weather down there is hot and sunny at the moment with temperatures cruising around 30 degrees Celcius. I wonder how this will impact the insulin in the pump, since I probably will not wear too much close to cover it... I have brought my insulin pens too, though, so if it doesn't work with the pump, then I can just go back to MDI.

I will be back in the beginning of June - with a nice tan :-)

BG's to piss me off

While the week in Prague generally went very well BG-wise, this last week has been a struggle of keeping a steady, and not too low level through the day. I have had too many values below 70, but even when such a value occur before a soccer game, and is treated accordingly, I have not solved the problem about high BG's afterwards. I find it incredible annoying, not to be able to keep it in range even when it's fine after the game. Mostly, I will be a little high afterwards, probably due to being disconnected for more than 1 ½ hour. For instance, we had a game in the weekend. I was low (2.9 [52]) before going out, so I had a four glucose tabs and a dried fruit snack to cover that (it was only about 1 ½ hour after lunch, so the bolus for that was still active in my system). After thoroughgh warm-up, I got the first half (45 min) of the game on the field. When being substituted at half, I reconnected and watched the rest of the game from the side - with the rain soaking us and temperatures around 12 C with a good wind to make sure we would cool down quickly! After the game I tested 12.3 (221), which I did not really get, but anyway, I took 6 units - something that would normally drop me almost 18 mmol (320), but when I retested before dinner an hour later I was up to 14.6 (263). Grrr! Why?? Being quite angry with this apparent "insuliresistancecsyndromeom-following soccer-games", I bolused 9 units for the dinner, which of course send me down in the 4 (70)-range later in the evening, but it appeared to work because I went to bed with a BG of 5.5 mmol/l (99) and woke up at 7.2 (130). Anyway, I have tried different alternatives to deal with the usually higher BG's after a game (I have managed to land at 6.3 (113) after a game, only to sky-rocket to more than 17 (306) only a couple of hours later), but so far it hasn't really worked satisfactory. I must admit that I am a bit puzzled about it, becauspracticese (1 ½ h) is usually no problem at all. Because of this I don't really think that it is just a matter of hormones (adrenaline) with the games. I have tried using Lantus like in the un-tethered regimen, but that did not really do the trick, so now I am actually considering involving Actrapid (Regular) before games, because I am used to handle that, but it does annoy me to have to grope through the darkness in order to find a stable solution, not to mention the reluctance of my diabetes nurse to the fact of involving other types of insulin than the NovoRapid given by the pump. So any ideas, comments or experiences on how to deal with sports when disconnecting, would be highly appreciated.

Tour de Prague

Walk on Charles Bridge in daylight

The trip to Prague was not all business. We did have time to enjoy the beautiful city. Wednesday we spend the whole day sightseeing. We started out heading for Charles Bridge (Karlov Most in Czech), to see it by daylight. On our way, we encountered an exhibition of sculptures in one of the city squares (see pictures).








Me at a sculpture outside a historical building

Some of the sculptures of one of Pragues squares

Charles Bridge and its surroundinggs are totally different in daylight. The bridge is crowded with tourist, street vendors, and beggars. We crossed the bridge to go to the other part of town with the castle and president palace. It took a lot of steps to get up to the castle, and at the top we stopped at a stand with a sign encouraging people to contribute to a project that should give mentally ill people of Prague better homes than the hospital they are currently staying at. For 100 Czech koruna (equals approximately 25 Danish kroner or 4 dollars), you would by a clay brick that would be used for the chimney or stone tracks at the building. We bought 2 bricks, decorating them for others to see that delegates of KMEB, Odense, Denmark contributed to the project ;-)

We visited a couple of churches on our tour, and here we experienced how groups of tourist, sometimes young people, other times older ones, would suddenly arrange themselves in rows with a conductor in front of them and start singing, testing the acoustics of the church. As soon as they finished their great performance they would disassemble as quickly as they assembled in the first place, looking like a group of tourists and not an awesome choir. Amazing!

In afternoon we headed back to our hotels to prepare for the welcoming ceremony of the congress that we were attending. We wanted to put up our posters at that time too, and as the others had posters printed on fabric, these needed to be ironed. My poster was printed on photo paper, and when the other posters had been ironed, we rolled these up around my poster to carry them all in the tube mine was kept in. The welcoming ceremony was about an hour in length, followed by a reception. Having walked a lot that day, all of us could feel our feeds at the reception, but it did not stop us from going out for a late dinner afterwards - only using the metro to get from the congress center to the center of the city, otherwise walking :-). The next day we were gifted with pedometres from one of the companies in the exhibition area of the congress. The company had a competition where delegates wearing the pedometres could come to their stand to show how many steps they had walked in a day, and if enough win a price. Learning this, we couldn't help being a bit annoyed that we had not had these pedometres when we went sightseeing the day before :-)

Back again

It has been a while since my last post now, due to the conference that I had to attend in Prague, but this just means that there is so much more to blog about now :-) The last days up to our departure was rather busy with meetings, poster finishing and printing and so on, which is why I didn't get to post anything during those days. We set off for Prague last Tuesday, having to catch a train at 7.30 AM in order to get to the airport in time. We arrived in Prague in sunshine and 23 C, and managed to find the right bus, to take us to the metro to get to the center of the city where our hotels were located. Now, even though the bus departed from the airport carrying many tourists, the information given through its loudspeakers were in Czech, which neither of us had any knowledge about. We knew where we had to get of, but because that was at the end station, and both the information about where the bus was heading as well as the name of the next stop was given through the loudspeakers, we misinterpreted the information and got off to early. Standing at the bus stop, we quickly realized that and luckily the next bus would arrive 10 minutes later, so in the meantime we laughed a bit of ourselves while we "synchronized" our mobile phones, so that if we were to get away from each other later on, we could send an SMS or call. We joked about picking up our boss, Moustapha, and his assistant research professor, Basem, who would arrive the next day, and getting them off the bus at the same stop to "synchronize" their mobile phones as well :-) We didn't do that though.

The whole KMEB delegation at a late dinner Friday. From the left is Jorge, me, Basem, Sijranke, Pernille, Moustapha (our boss), and Moustapha's wife, Mette. Amer is behind the camera.

Standing in the center of Prague with all our luggage, our first quest was to get hold of a city map to help us locate our hotels. We were 5 people, two guys and 3 girls, but we had not managed to get the same hotel for our stay, so the guys would be in one apartment hotel, while Pernille, Sijranke and I would be in another apartment hotel. It took us a while to actually get hold of a map, and still we had to ask for the way to our hotel. Because we were approaching 3 o'clock in the afternoon, not having had lunch yet, we decided to drop the luggage in our hotel, go get some lunch and then find the guys' hotel afterwards. After this late lunch, we went shopping for breakfast the next days (breakfast was not included at any of our hotels, but as both of them were apartment hotels that didn't matter much, because we had kitchens to prepare our own breakfast in), and located the guys' hotel, which turned out not be very far away from our hotel. After getting settled in our hotels we went out to look at the beautiful city of Prague by night.

Sijranke, Amer, Jorge, and Pernille standing on the Charles Bridge of Prague

Me, Jorge, Pernille, and Sijranke at Charles Bridge the first night in Prague

The conference officially started on Wednesday 10 May, but having looked at the program, we decided that clinical lectures that were on, did not really have our interest, so we went sightseeing in Prague the whole day instead - I will tell you about this in another post. We registered at the conference in the evening to attend the welcoming ceremony and reception, though, as well as to put up the posters of our scientific work.

Me at my poster

With this I will end the first part of the "conference in Prague"-tale, stay tuned for the parts to follow :-)

Soccer and pumping

The past weekend was pretty busy. Saturday I had an away soccer game in the afternoon, and Sunday we had to go to the confirmation party of Jimmi's cousin. In this program I had to try to fit in at least 1 overnight-to-lunch fast for the nurse to evaluate my basals at the appointment today. I started a fast Friday night, but had to stop for "lunch" at 10 AM, because I started feeling really hungry and thus decided to test: 3.4 mmol/l (61). Despite eating well and cutting back insulin, the low trend continued and I was only 2.7 (48) when I tested before preparing for the game. Grrr...! Well, glucose tablets and my preferred carbohydrate-containing sports drink of orange juice and water 1:1 (I prefer to just drink water when I practice, but when needed I have found this combination of juice and water to be useful) in combination with the fact that I always disconnect when playing soccer did the trick and I landed at a satisfactory 6.4 (115) after the game. I didn't eat anything at that time because dinner was just about an hour away and I didn't want to spoil my appetite for Jimmi's chicken roast ;-) During dinner I started feeling uncomfortable, though. In the beginning just tired which I thought was just due to the game and bike ride, but then a subtle nausea started showing its ugly face. I didn't finish the meal that I had bolused for but hit the sofa instead. As I didn't feel better and also started feeling thirsty, I suspected that the BG was not where it ought to be. Surely not! At 7 PM, just 2 hours after being 6.4 upon more than 2 hours of soccer, I was 17.7 (318) with ketones starting to show up :-( Based on my experience with a leaky tubing earlier that week, I decided to do the correction with a pen, just in case this was a pump and/or tubing issue once again. I had just done the correction and tried to drink some water to quench my growing thirst when my dinner decided it was time to resurface! Why does such things always happen after you bolused/corrected? Needless to say, this meant that my BG's cruised rather low the rest of the evening, but luckily I managed to pull through without help from others. I discussed the episode with the nurse today, as this was exactly one of the precausions that I have had about pump therapy. She couldn't explain what had caused it, and I really have no idea either. I can't say that it couldn't have happened with MDI's, just that I have never in my more than 16 years with this experienced anything like it. It is my general experience that my BG will rise after soccer practice and games if not compensated with insulin, but I have never experienced such discomfort due to a BG that has only been high for a short amount of time. Only with continuous high BGs as at the time of my diagnosis and the end of my honeymoon period, did I feel that unwell.

Apart from the issues mentioned above and in previous posts, I am slowly adjusting to pump therapy. I actually enjoyed being able to go through the 3 course-menu lasting more than 4 hours at the confirmation party without having to either inject several times or risking to bottom out between courses. The next big test for me will be a trip to Prague next week. I am going to a conference on calcified tissues, presenting a poster with some of the results of my Master thesis - details will follow :-) The nurse provided me with a pump certificate today to circumvent problems at the detectors in the airports. They are actually still working on making this certificate more convenient. For now it is just a bunch of papers that can be cut into smaller pieces and fitted into plastic covers about twice the size of a credit card. Most of the pages are in Danish, though, being more like a short guide to the pump user. The language of the certificate written in English is quite poor and not that informative yet, but I guess that it does contain the most important information about the pump being a medical devise that is not to be taken away from me, and a referral to the Endocrinology Unit at the hospital in case of doubts.

Pump issues

As mentioned in one of my previous posts, I have agreed to try an insulin pump for 3 month. My diabetes nurse has tried for years to convince me about this, but it was a combination of several things that finally made me say, "okay, let get it over with then":

1. my boyfriend suddenly turned around, thinking it would be a good idea - so now the pressure was on me from several directions!
   
2. the fact that maybe, if pump therapy should really improve my daily regulation, now would be a good time to test that in order to finally be able to convince my boyfriend that going to Denver to do a Ph.D should not make him worry, if I deside to do that, even if he does not feel like going with me
3. I am going to a conference in Prague in the beginning of May, and this would enable me to test and compare the challenges of travelling with a pump vs. pens

The reasons why I have been reluctant to try the pump were not that I could not see some advantages and posibilities of this sort of therapy, but mainly the fact that I could also see some disadvantages and difficulties of it, which didn't really excite me. A few of the latter mentioned have turned out to just be prejustices, now that have been pumping for almost 3 weeks. However, yesterday reinforced another of my pump prejustices: The one about the need to test frequently and ALWAYS have a back-up plan at hand. Yesterday started out okay. I was 7.8 (140) before breakfast, and I used the bolus wizard to estimate the breakfast bolus of 5.6 U. Because I have not come to trust this wizard function completely yet, and because I had a suspicion about being too high later that morning, I tested again about 2.5 h after breakfast: 17.1 (308)! WTF!!??? Although I suspected that I was high, I did not imagine I would be that high. While evaluating posible reasons for this, I took a correction. I inspected the site, wondering that it looked a bit moist, but maybe that was because I had been sweating a bit on my bike ride to the university earlier that morning. When the pump had given the correction I inspected the site again, though, and I wasn't pleased with what I saw! Now it was clearly wet and the smell of it let no doubt that the site was somehow leaking! Great, just one of my precausions about pump therapy had been confirmed. I did not have another infusion site at my desk, but fortunately the pen that I used to use beforehand was still in its place, so I turned to that instead. However, I had no idea how much, or how little insulin had actually been delivered by the pump, so I would have to guess on the correction and the bolus for lunch later. That went fairly well, though, despite going low before lunch (3.0 [54]). The rest of the day I debated with myself about whether to insert a new site when I got home, just prior to leaving again for soccer practise, or just leave the pump off until this morning. I was seriously tempted to do the latter, but I ended up inserting a new site when I got home anyway, and fortunately it seems to work as it is supposed to (*7-9-13*). I can't help wondering about how sane it actually is to miss injections!! You woundn't think that would be a posibility, having cursed the inconvenience of them on and off during the last 16 years ;-) Still, the experience confirms that the pharmacy that you have to bring along when on the run will be even more voluminous when using a pump, and I must admit that I think that I will rather carry the pens along with me than having to carry extra infusion sites, syringes, insulin bottles and so on. After all the pens easily fit in a pocket or a bag, while the pump supplies will require cargo pants with multiple large pocket or a bag with a compartment dedicated to the supplies to cover prospective issues of insulin delivery :-)

Copenhagen trip

Monday I went to Copenhagen. At a career fair at the university a couple of month ago, I took part in a competition at the stand of my labor union - and I won! The prize was a 2 h appointment with a career/competence counselor. This appointment took place at the union's headquarter in Copenhagen on Monday. I didn't really knew what to expect from it, but it was quite interesting. I had talked to the counselor on the phone prior to our appointment because he would like a test as starting point for our conversation. So I took this test akin to those that some employers use at interviews with new possible candidates for a job. This was done on the Internet, and the counselor had then printed the result which we could then discus. Although I find that most of these tests generally want you to choose between cholera and the plague, I could actually recognize myself and my way of being in the test result, so I guess that was good. I tried another test like that on a job portal on the Net a while ago, and the result of that implied that I was the same type of person as Charles Darwin, Albert Einstein and Marie Curie, and thus would fit well in a job in science. The test of the union also showed that I have some personal qualifications that almost only fits with what is wanted for scientists :-) This actually please my, because I would really want to be a scientist!

Because I do not go to Copenhagen very often (I don't really like moving around in the centre of Copenhagen with all the noise and traffic), I had made sure that I would be able to meet with my best friend, who have been living overthere for almost 7 or 8 years now. We went out for lunch and spend about 4 h together until we had to split up for her to catch an appointment with her chiropractor, and me to catch a train back to Odense. We both agreed that we ought to meet more often than we do, usually we only mail each other or talk on the phone for hours, but it is certainly more enjoyable to meet! We got to now each other on the hospital of Holbaek more than 16 years ago. A the time of her diagnosis of Addison's disease and mine of diabetes. Ever since we have kept contact, frequently discussing the inability of some doctors and other health personnel to understand such chronic ailments at the level of the patient, you now, the fact that theory and practice does not always match as perfect as most doctors seem to believe.

What a week!

This week I haven't had time to up-date my blog or to read other blogs. Tuesday I had a meeting with the guy whom I though was my employer to be. The meeting went well, and we both expected that I could start up on May 1. However, it turned out that the agreement on jobs with wage subsidy should be approved not only by the employer and the employment exhange agency, but also by the head of department and the trade union representative. The head of department was pleased with the agreement, but the trade union representative was not. He would not support this kind of underpayment of highly qualified young workers as he said. If I could be employed as a research assistant on regular terms and conditions, he would support it, but he would generally - because apparently it was the policy of the faculty - not accept jobs with wage subsidy unless the applicant had been unemployed for a long time due to missing qualifications. I can see the situation from his point of view, but I don't think that he quite understands how it works in the scientific community. There is just not an unlimited amount of money to be spend on hiring new people, and when there are money for hiring then the leaders will usually look around in their own group of students or research assistants before taking in one from the outside. I know of at least a hand full of people who would not be in a Ph.D-position in the groups where they are not, if it had not been for the wage subsidy offer. One of my supervisors from my Master's, Ole, was quite baffled about the attitude of the trade union representative too. Although the trade union representative's position on the issue meant that Ole would then have me as a candidate for two part-time positions as research assistant that two of his collaborators would want to pay for, he still felt an urgent need to react upon it - and I think that he will do just that very strongly! The conclusion for me now is that I am still unemployed, although Ole may be able to hire me again if his collaborators agree to it. Thus, I still have to look out for new possible jobs while finishing the paper that I need to write for us to publish some important results from my Master thesis, and the poster that I am to present on a big conference in Prague in the beginning of May. To make situation even more comical complete, I have actually been assigned a Young Investigator Award for the abstract behind my poster, which I will collect at the conference in Prague! How can you be about to publish something, be awarded with a Young Investigator Award and still have such difficulties in getting a permanent job and preferably a Ph.D-position?

This week I also had an appointment with on of the diabetes nurses out on the hospital to evaluate my first two weeks of pumping. The appointment was mainly focused on approving the changes I had made myself in the basal rates and the settings of the bolus wizard. I guess I must be a pain in the ass to some doctors and nurses because I tend to react when I am not satisfied with the regimen, and I hardly ever consult with the team until afterwards, but I am almost always correct in the changes that I make, so I can't help it. This time the nurse asked me if I had calculated the new carb-to-insulin ratio and insulin sensitivity that I had entered into the pump after being very unsuccessful in using the original settings that the nurses had calculated when I started on the pump. I had not, because do not know how they usually do that, but when she sat down to do the math, it turned out that my perceptions about these numbers were pretty darn close to her results - actually the variations were confined to decimal points! I am still not completely satisfied with pump therapy, but it is not fair to conclude anything based on only 2 weeks, so I will continue trying to get a grip on it. I am to do a series of evening-to-lunch fasts before my next appointment in 1½ weeks, something that I find quite hard partly because I cannot go back to sleep immediately after having been awake to measure at 3 AM and thus will be cranky if I have to get up early the next morning, but also because I am usually very active on a daily basis so I am hungry. I am half way through the 4 of these fasts that I need to do, but I certainly look forward to get them over with. Next Friday I also have an appointment with the dietician - actually the first appointment that I have had with a dietician since diagnosis, so maybe it is about time. I hope that she can help me with this new thing of counting carbs - carb counting is not mandatory in the general Danish way of diabetes treatment, only for those 0.5 % of the Danish diabetics who are in pump therapy it should be. We will see how it goes. I will try to post a bit more frequently in the week to come, but I dare not to make any promises about that ;-)

Hard work of Easter

Why is it that holidays are such "hard work"? You have to catch up on everything that you miss on working days, including family visits. It sometimes feels like you end up being more busy in the holidays than on working days. Thursday Jimmi and I went to see his mother. Jimmi's sister and her boyfriend as well as Jimmi's grandfather was there too. Jimmi's mother always make sure that nobody will leave the table hungry - i.e. she cook for a whole army despite only expecting 6 people for dinner! It is very enjoyable, though, although you are so full when you leave :-) We left quite early to drive Jimmi's grandfather to his house. He has been sick for nearly a year now, also loosing his wife in the middle of his illness, so he is dependent on in-home help on a daily basis, which means that he has to be in a certain times of the day, limiting his ability to go out for social events. I had to get up early on Friday, so I didn't really care that we had to leave early. I had the first soccer game of the spring season in my new club Friday morning, and as it was an away match we had to leave from the city center at 8.15 AM - about the time I would usually think about getting out of bed on weekends! I was quite excited about the game, mostly because I hadn't played one since October last year, but also because it would mean yet another new experience on how to handle thing with the pump, when I will not wear it on the field. I started as a substitute, so I could keep it on until the beginning of the second half of the match. It went quite well - no surprise as the pump was actually not even off as long as it has been during practice, so I still have no idea on how it will work when I am first choice as I would then take off the pump before warm-up and actually be off it for 1 h 30 min after that - a total of about 2 h.

Yesterday we had my sister, my parent, my grandparents and Jimmi's father, stepmother and younger brother over for Easter-lunch. It was a long day, but very nice indeed. It was actually the first time that my grandparent came to visit us. My sister and I moved to Funen more than 5 years ago, and ever since my grandma has wanted to get to see how we lived. It shouldn't be that difficult, because my father's youngest brother and his family lives in Southern Jutland and my grandparents go to visit them on a regular basis. Usually my father's older brother will drive them, which mean that they actually go right by Odense and should be able to take a quick turn off the highway for a short brake, but this have never happened, so yesterday my parents brought my grandparents here. My dad took them for a ride around Odense for a sight-seeing of the places where Maiken (my sister) and I have lived/are living and working before they arrived at Jimmi's and my place. They were very happy about it :-)

Today it is time to relax a bit. I haven't had time to read my newspaper the last couple of days, so I will sit down with them today. The weather is quite nice today too, so I will probably also want to go out for a bike ride to burn some of all the calories of the last days' Easter-lunches :-) In the afternoon, Jimmi and I have tickets for Circus Dannebrog. That should be nice too.

Plans for the future - part 2

Last week I had interviews with 6 different possible future employers. All of them went well, but three of them were more interesting than the other. I was very difficult to decide which of them to turn down, but I managed to inform all of them about my final decision just before Easter. I have chosen to start as a research assistant in a group out at MBC. This position won the race because the leader of the group, who is a very sympatic guy, offered me my own project to start on. The project would lean agains one of a newly started Ph.D-project, but deal with another protein. In general, I see great opportunities for future research, including a Ph.D-position, in this group. They work with different recognition molecules of the immune defense, some of which are involved in autoimmune disorders. They were actually in need for a person to assist the former mentioned Ph.D-student, because her project involves use of mass spectrometry - in corporation with my supervisor from my Master's in fact - but she did not know much about it. I look forward to start a project in this group, getting more experience in experiments with genetic manipulation and research animals as well as being able to contribute with my knowledge about protein chemistry and mass spectrometry. I haven't given up upon the Ph.D-offer from Denver yet. In fact I see the possibility to combine the project in MBC with that from Denver, thus even enabling mass spectrometry to be part of the thesis, which was not readily an option before :-) Of course I don't know if it will be that way, but anyway I hope to be able to go abroad during my Ph.D - not least to get back on Jimmi for not going along with it in the first place ;-) I love him but I cannot help being a bit disappointed that he hasn't been willing to a least give it a chance and go with me to Denver to look at it before a final decision is made.

Today was the first day of the Easter holidays. This afternoon Jimmi and I took Jimmi's younger brother to the movies for Ice Age 2. That was great fun! Well until the last 5-10 minutes of the movie where I started feeling very tired. I acknowledged this as a symptom of hypoglycemia although I didn't quite see the reason for it with all the popcorn we had consumed during the movie. The movie theatre is located in the central train station of Odense, so before I went for my bike to go home I found a bench to check my bg. 1.8 mmol/l (32 mg/dl)! Ups! Down with 5 glucose tablets and a cracker waiting for it to work before getting on my bike for the 4.5 km ride home - with the wind very much against me! The bg is now back up on a nice 4.7 (85) and I am ready for this evening's Easter get-together at Jimmi's mother's. I am still a bit annoyed about that low, though. A couple of weeks ago my diabetes nurse along with Jimmi managed to talk me into giving the insulin pump a try. The nurse has tried hard to convince me the last 4 years, and it is not that I don't see the advantages of the pump, but I also see some disadvantages, so I am not that fond of it. Last week I was then started on the pump for a 3 month trial. I know that it takes time to adjust the basals and other routines when switching insulin regimen, but seriously, I feel like I have had more hills and valleys of my bg this last week than the last half a year on shots! That is very frustrating, but I have to be strong and go through with this, comforting myself with the fact that if I cannot adjust to this, I can go back to shots in 3 months and my nurse promised that she would then stop mentioning the pump for another year or so. I guess to understand why I talk about this as a trial, I need to inform you a bit about the Danish medical system. Danes, who needs medication, are covered by an "ingenious" grant system. The more medicine you need the less you have to pay yourself, but the system restarts itself once a year making you start all over paying the full price yourself again. Anyway, as for supplies for diabetes, all type 1 diabetics gets their testing supplies, needles, lancettes and so on for free. Most Danish diabetics on insulin use insulin pens to deliver the insulin, and since pens to be used with insulin pen-fills are free, so are the pump - at least for the diabetic. The costs of the pump and all its supplies are covered by the hospital ordering it, so I only have to pay for the insulin in a different form to use the pump. So far I am not convinced that the pump is the ideal solution for me, but maybe I will change my mind once the insulin doses have been adjusted to fit my daily routines.

That's it for now, I am of to the Easter get-together!

Plans for the future?

This is always a difficult question to answer. To understand why I blog about this, I should mention that just finished my Master's last fall so I am in the beginning of my career. I finished with top grade (13 on the Danish scale), which made everybody assume that I would be able to pick and choose between jobs or Ph.D-positions. Sure I was appointed as a research assistant two weeks after my exam, but the position was time-limited - only 3 month. There was a chance that it could be prolonged, but this has not happened due to financial issues. Though of course it was sad to exchange salaries for daily allowance, I can't say that I am sorry that I could not continue with the work, because it was not that inspiring or challenging. When the 3 month was almost out, I got an unexpected mail from a scientist at the Barbara Davis Center for Childhood Diabetes. He is Danish but has been working as assistant professor at UCHSC in Denver. He is the head of a small research group working with developmental biology in the hunt for a cure of type 1 diabetes. He mailed me because he had read a popular paper for which I was awarded the Herbert Price 2005 of the Faculty of Natural sciences, University of Southern Denmark (SDU), and wanted to give me some credit for it. At the same time he wanted to tell me a bit about the research that he and his group were doing, as it might be of my interest. It was, and so was his open offer to maybe do a Ph.D in his lab. I have been in contact with him on a regular basis the last couple of month. It is a big decision to go the US for 3 years, and my boyfriend certainly does not share my enthusiasm about getting such an offer thrown at you. Jimmi (my boyfriend) is not willing to move nor will he fully accept the possibility that I would go by myself and then follow the courses of the Ph.D program here in Denmark whenever possible. He has changed his mind about it regularly, getting a little bit closer to a compromise, but not enough, and it kind of disappoints me that he cannot support whatever decision I will get to, trying to make things work as smoothly as possible. I do not think he quite realizes how big this opportunity actually is, and how deep impact it will have on my future career to get a Ph.D, and especially one obtained away from Denmark. With this you will have both a Ph.D and experience from living in a foreing country, which is what many employers like to see. It would make it so much easier to get a job in a private company or in the academic society when returning to Denmark. I must admit, I was not so sure about going away for 3 years when I first got the offer, but the more against it Jimmi is, the more I want to make it happen, despite the difficulties it will entail.

It would be easier to say no the offer from USA if I had an equal or even better one from home. I do not at this point, but of course I have been seeking for it. I have applied to several position, but I must admit that it has mostly been because I need to be able to prove that I am actively seeking employment rather than because interest. Last week a friend of mine from the lab told me about the possibility of getting into a research lab or a company by wage subsidy with the possibility to continue in a Ph.D. position afterwards. She did that herself, and I know of a couple of other people who have also used that trick, but I was not aware of the actual offer and the rule about it. We sat down and made a list of more than 20 scientists and companies that might benefit from getting a skilled cand. scient in biomedicine with experience in mass spectrometry into their house at low costs. I mailed all of them Friday, receiving the first answer only 10 minutes later, and over the weekend I got positive feedback from a total of 6 people and companies who would like me to come by for an interview. Thus, the first three days of this week has been very busy with 3 interviews Monday, 2 yesterday and 1 today. 3 of the interviews are of particular interest to me, so now I have to sit down and make a decision on where to place my bet: 3 years in USA, employment as research assistant with open possibilities to obtain fundings for a Ph.D in two different groups at the Medical Biotechnology Center, Odense or in a small private company. It is going to be tough!

Born to be a doctor ;-)

In a break between writing on a paper and searching for employment, I just came across a test on the Internet. The overall question of the test was which advanced degree you should pursue in your career. I answered the questions, and here is the result: I was born to be a doctor.

You Should Get a MD (Doctor of Medicine)

You're both compassionate and brilliant - a rare combination. You were born to be a doctor.

What Advanced Degree Should You Get?

I found that conclusion rather amusing as I actually considered going for medicine when selecting education years back, but went for biomedicine instead because I was not sure how comfortable I would be treating other people’s casualties and because I thought the perspectives for biomedicine were just perfect for me. Students in biomedicine must attend some medical courses in concert with the medical students. In these courses, we were often regarded as medicine-wanna-bees, who didn't have the grades to be accepted for medicine. Because of that the satisfaction was even larger when you were able to outsmart the medical students and instructor - which did indeed happen from time to time, mainly in the biochemical areas :-) I have never regretted that I chose biomedicine for my career. I still think it was and is the obvious choice for me, and I am fully confident that I will get a career as a scientist. e work, tFor the time being, while I am pursuing a PhD-position of interest, I still hang around in the lab where I did most of my Master's project, helping other students and keeping in touch with the principal investigators. My highest wish both when choosing education and also now, is to become a scientist working with the quests of diabetes. Today I am also keen to include proteomics and mass spectrometry in though, but I would still prefer if it could be in combination with some disease, e.g. diabetes.

About me

I am a 28 years old Danish girl, born in the middle of Zealand, but living in Odense, Funen for the last 5 years. I finished my masters in biomedicine last fall with top grade (I am very proud of that, it took a while to realise that it was actually true). Biomedicine is a combination of molecular and cellular biology and some medical courses enabling the candidates to work as scientists in corporation with medical doctors, actually being able to communicate with the doctors in their language ;-) After my exam, I worked on a time-limited position as research assistant, but am currently unemployed, though having a great offer that I am considering. The fact that I haven't just accepted the offer is due to personal issues that I will introduce you to in a later post.

I was diagnosed with type 1 diabetes 16 years ago. Ever since, January 16 1990 has been D-day in my life. Thinking back, the symptoms started around Christmas 1989. I remember drinking a bit more than usual, and that my parents noticed it, but thought it might just be because of the Christmas food. I wasn't. In the following weeks my thirst became more severe and I needed to use the bathroom more frequently. I used to be able to sleep through the night without having to get up for the bathroom, but the night before I was diagnosed I was up 5 times to pee and drink, so I did not sleep much. I was tired, thirsty and did not feel like eating anything. My dad made me an appointment with our doctor in the afternoon, and after doing a finger stick, the doctor sent us to the hospital as my BG was too high for his meter to read. I remember that I cried all the way to the hospital (45 min. drive), thinking that this was just so unfair. I have had asthma and allergies all my life, and from age 4 to 8 I had petit mal epilepsy (the kind characterised by frequent so-called absences, not seizures), so I certainly thought that I had already taken my share of sufferings, but I was obviously wrong :-( So, I was admitted to the hospital and stayed there for 14 days. One of the things I remember most about that hospital stay was this nurse telling me to remember that despite my new diagnosis I was no different than my peers. Well, how are you to believe that when you are told that you must be treated with insulin given at certain times which means that you have to eat at certain times too, and because the regulation of the doses should match my typical days I would have to eat my hot meal in the evening as opposed to all the other kids on the ward, who had their warm meal at lunch? My designated meal plan in the hospital meant that I could not eat at the same time as all the other kids, and that the hot meal I was to have for dinner, needed to be heated in a microwave oven placed on the adult ward. Now, I have nothing against microwave dinners as such, but there are certain food items that are not suitable for reheating in a microwave! Gravy and ordinary potatoes tend to become very boring with a rather unappealing taste when they are reheated in a microwave, and as hospital food are not too interesting in the first place, the dinners on the hospital was not something that I looked forward to each day. Luckily, I was in a room with 5 other girls, one of whom I became very good friend with (we are still best friends today). This girl also had a special diet because she had been diagnosed with Addison's disease and had lost so much weight that she actually appeared anorectic and sort of needed to be fed up again. She and I could share our experiences with the food like none of the others :-) Finally, I was discharged on the last day of January. Being at home my parents were very attentive. My dad still hung on to the hope that the diagnosis was wrong and as he watched my sugars the days after discharge, he slowly began lowering my doses (I did the injections myself, but under my parents supervision) without telling the hospital. I had the first appointment with the hospital doctor about a week later, and when he learned what my father was doing, he was worried but he could not do much about it. My dad continued lowering my doses, and on day 10 after my discharge I was off insulin. Still monitoring my BG's frequently and watching my diet, although not hysterically, I was off insulin for 7 month. Man, those were the best 7 month after my diagnosis! Unfortunately, it could last and in September hyperglycemia showed its ugly face again. At that time I had changed doctors because my parent and I weren’t really satisfied with the first one. The appointments meant a 45 min. drive, and once we got there, we would usually have to wait approximately 30 more minutes before being called in for me to be weighed, have my height checked, and being asked how I was doing. This usually took no more than 5 minutes, but as it required an additional 2 hours wasted on driving and waiting, we wanted to find a doctor closer to where we lived. The hospital in our home town did not have pediatrics, but, asking kindly, I was allowed to enter the adult ambulatory anyway. There I was set up with the best diabetes doctor, I have ever met. None of his successors had his qualities, so it was a great loss when he got a new position - on the hospital we left :-( Anyway, he set me up on a MDI regimen (when I was diagnosed I was put on NPH twice a day) with Actrapid and Insulatard (regular and NPH) and slowly titrated the doses until they fit my daily activities. I was on that regimen with quite good regulation HbA1c-values 5.1-6.5 % for 13 years. When I started university, however, I began having trouble with my fasting values. I could go to bed with nice values of 6-8.0 mmol/l (108-144 mg/dl) but would, with very few and unexplainable exceptions, wake up 13-20 mmol/l (234-360 mg/dl). The days that I wasn't high, I was usually below 3.0 mmol/l (54 mg/dl). It was very frustrating, because I did not feel well at the high values, and if I did not take my insulin, correcting for the high, and wait at least 45 min. before I ate, I would be high (i.e., above 200 mg/dl) at noon too. So, I had to wake up quite early to give the insulin time to work, and I sometimes ended up over-correcting the high, going low later in the morning. Some of these low were quite severe, and I had several trips to the ER during those years. The endocrinologist I got to see when I moved to Odense did not think the problem could be so big because my A1c's were still around 6 %, so it took a while to convince him that it might be a good idea to be hooked up to a CGMS to see what was actually happening during my nights. I had tried to set my alarm clock to measure in the middle of the night, but it didn't help much, as the value there was usually fine (below 10 mmol/l (180 mg/dl)) and then when I had to get up 3-4 h later it would be about twice as high, plus I would be cranky because my sleep had been disturbed (I am unable to go back to sleep immediately, it usually takes me 30-60 min to do that when I have been awake to measure, not least because I will eventually speculate if the reading was too low, too high, perfect, or whatever). Fortunately, the endocrine unit at the University Hospital in Odense (OUH) had the CGMS available. I was hooked up, and when the readings came out the skilled nurse scratched her head and looked at me in understanding as she could certainly see my frustration about the reading because there really was no pattern over the nights. I happened to be on the CGMS with one day of normal fasting reading and the other three with high readings, so in general the days were quite representative. In corporation with the nurse, Alice, I tested different changes, none of which were effective though. She suggested that I tried an insulin pump. The pump is not a very common way of diabetes treatment in Denmark yet (only about 0.5 % of the type 1 patients in Denmark are pumpers). I was not very fund of the thought, so we also discussed other possibilities. We ended up agreeing that I substituted the NPH with Lantus, which at that time was not approved in Denmark, but was available through different test centres, including OUH. This change was a change of the world to me! Not only was my insulin doses over the day lowered, but for the first time in years I would wake up in range (4.0-7.0 mmol/l - 72-126 mg/dl) almost every morning. That was great. I have been using lantus in combination with regular and NovoRapid for 2.5 years now and it still work nicely most of the time. I do have intermittent troubles with hypoglycemia, though, and despite them being far less than before the change, Alice is still nagging me about at least trying the pump. She would like to elevate my A1c just a bit to 6.0 %, my last one was 5.8 %, to avoid the lows without any significant symptoms that I still experience at times. I guess that I have some kind of hypoglycemia unawareness, although it is not absolute, because most of the time I can feel when I am dropping, but the symptoms are weaker than they used to be, and I usually need to get below 54 mg/ml before I feel them. I have my next appointment with Alice the coming Tuesday, and I promised that I would really consider trying the pump. I have considered it, but I haven't come to a final conclusion yet. I guess that eventually I will end up trying it, and maybe like it, but right now, despite the advantages that I do see with pumping, there are some disadvantages that I cannot help focusing on. Most significantly is the fact that you are to be hooked up to this device 24-7 365 days a year. I know that you can disconnect when required, but still. Although I know that others wear their pump doing sports, I do not feel comfortable with the though of wearing one when I play soccer. In season, I have two practises and 1-2 games every week, and if I am to disconnect every time then what is the purpose of pumping? I don't know. Maybe it is just me, and maybe I would change my mind if I tried it, blaming myself for not having taken that step long before, but I am not confident yet.

Well that was quite a long introduction. I hope I didn't bore you too much :-)

I have been reading different diabetes blogs, primarily American (e.g. Kerri's Six Until Me, Scott's Diabetes Journal, Alison's Lemonade Life and now Everything related, Megan's This is My Life, and Sandra's A Shot in the Dark), for months now, and I find it very interesting and inspiring - just the fact that there are others out there dealing with the same health issues every day. So now I decided to join the party myself. I am, contrary to most of the members of the OC, not American. I am a native Dane, and of course I could choose to create a blog in Danish. The reasons why I haven't done this is mainly that there is not such a great tradition to blog in Denmark - at least I am only aware of a couple of diabetes related Danish blogs at the moment, although there may be more - but I also see blogging in English as yet another great opportunity to improve my English vocabulary. I consider myself to be rather good in English, but as it is not my mother tongue there is always room for improvements :-)